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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730278096e8f5c9a6198d76f21eacc2a1d1899beac526a3e44bdd3cc835b32da' 
  AND token = 'YEREZ0uY5Yvm0V1/1jfUgxABRQ3QY88anson4D5UrEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}