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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddb5d43b50234b9c8960ad83b6122708ae84b68238d5f9ec61b79022f5b835e0' 
  AND token = 'dkjOHf66w6Y/Q7q/mHQDJXT1xtn/jYql3Pnp1h3rEM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}