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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '412271900c813cb58e56325edb6d729d389c387c6e903f13680098a6798fbdbc' 
  AND token = 'PVbvJptT6q7Z999D+/d9F6lWJMh+N6flIbPB/MJKDmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}