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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b51720fba058813ece7e16c56f12515d0f51edab3547f016d99f817e38b9443' 
  AND token = '6gETeF2oFzNfZtUbbTTw4lcBvkqyM1vOVP9Ls0cDrdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}