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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19acd28fc51eb1a34c4feddac7acb38cf44b1ef37fd51a3dbcf584795a007319' 
  AND token = '2BIF2L+Y+D0tG1Bu2MvnPvVYQwKzaikzteZPrF9nKKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}