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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33fafe64fce6b3a1c4bb57cb5a6fabbfa827f35aed04c7619dbf208f1afb9412' 
  AND token = '7sLIM9zv6HS+g+pBf7kKte1UOZNDQcw0o0tgm01aQmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}