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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '627f1f7888f4290fc55bbd25e2294c9d6c423083b805626dcce89037dee8678a' 
  AND token = 'aQ8PfGpttaGAc+jCNGEjY2Utgwq3kX+Yj2bmvHUDRMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}