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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97e166c533b3fbbb8dfb992abf8c301d51e18f0cadf2fff03c1e587388afa292' 
  AND token = 'q6DaXrZ296sQc1k+PfP4ZSwM2NlUHQ5qlZBtI1tJh2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}