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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bc4a3a7321343c13d7ee4a81af1e15203a187ce74de75d8c050d06927047d2e' 
  AND token = 'IimMT069/0/BuIVAGVLvd88p3t7xXom08EkxihV8rws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}