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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dc253984c6ca07c2624ef4a897894029356e58f912387181460e61c22dac7c5' 
  AND token = 'Fqan5UUJfgd8GYbn3+tsJt3HTJ35eQCgs1yiAEtjUTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}