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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '203904b87d994370b81dcb9e0e4b6fb001377959944aa1adbd6f378103bc4273' 
  AND token = 'QW8P0nSQGV+jIMhg+kzcqPzX4y1r32wAaoA5PozLyTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}