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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7afb483ebffb183565629fb4460688c60a87116ddaa2448d755b287b7f7273a' 
  AND token = 'o6coAShTB2ZynRl7sGf+cBJBNyXy/Rl2HkcKrNco0Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}