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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cdb144e6e4fac4f78375711bcf510da8aafa9241dad657b3cd1202603eef2c0' 
  AND token = 'EEbyRXalpx8JlgNw46SVxDIjmhXhGbzOobPktj7VQWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}