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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f29e0546313052045c842cd9a74ee3ed7eefc5b00036781bc0c74c7e7cd1b02d' 
  AND token = '+NegH3xoq9K8dZCjaDvK7yWhvYbl+g6UUrTsi9BuJxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}