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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b9c0d33c8c425d9614323904958031cf6fd889beeec459bfe10f8451692ede' 
  AND token = 'TW72UpQbBR4DNMAYWgJRiYub0QmkXhMZ+BcqyfZgc4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}