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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59749b7b8cf5e5cd9330a5fa30ab8bb3dbb5a6a01d3f457daf54711f5582c981' 
  AND token = '5cdaua1LW5/zsT+BJ7jdlRomGg5y70byReIFOBdLNyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}