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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8ae3cfd81ecb36fe32a4d0a72256ca85134ecb69d70d4969d4f32e370320d27' 
  AND token = 'ua9296JRb9N64su7r2dpEQ1Jow8mPdKErDLJItOeedc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}