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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d991a23213ade7813a7a4dda385dc974f12e568a39337eafd2caedc4515f33' 
  AND token = 'RKhazGqu0wNnYX5DOPcds128YTXNTNs6Mod38EONNuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}