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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ece96b66e7374dcd3a3c2d670eae84b30dfe1e6ea51738c06863d49afd5c2bb' 
  AND token = 'Ni2qJsQ8te7dTlxuWDsHrGcCU8oK1WCc4FJHJfxH29I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}