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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eea72b3eed0a2400b6e17f03bdef917d7e9e0f208c124780d3820d5ee3ed894b' 
  AND token = '81S7tpB0lYkEc7MrrmzpOpCGU77MgUFGmjUhFTaGdWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}