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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de1e8729cafb8a6b6820cf463c20bc2dedece354415b97d88f05ec2e4505d287' 
  AND token = 'y5AQhOV5ykAf8Zr9RBnnZWW4mEBJPjlLk8jwpXEzOT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}