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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5747ca1aa9f06c2bce57ec8da3ee4720bd5b2c3b03180fe365f7b87760ec383a' 
  AND token = 'uG0/jLXRMtLZXtqh2d3GJTSsAbm0UY4R46yOsw1P+TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}