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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b9dd79da9856a6e5cc68c5a79a2b0bf073bdcd6be922d54ae115157d2fc2298' 
  AND token = 'jroXKpwUa7XUeuTj7k0dW3WA26ZUr2UIFQ/3SB/NtrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}