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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffd7d3f5ac1cc74c2202833fd973e3f94adcdfbae5117de7236cde32c52d1182' 
  AND token = '3TQL3OnxXzTmIOec+Xli8fOSkADJ2BnnhevMtCp2P7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}