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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd305417f3c62d90f372055126b9f8f06e60b7a1e0b9d76e0032f8d207fc1c9bb' 
  AND token = '1Z69j/x7/BaJARiXWOXTWFbCOEnEf1Fjr5ghA9OBLE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}