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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cf19090dcaa0451aa6e1a67bd5a1b757c89161f7b4a3ec3bc607832c11afe7c' 
  AND token = 'qGYhZizBbwZEf2yfq/2ClnDFA3ZYTijyzFBnT8tS3Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}