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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2b51d0b48418c5597d5f7cc178d91541d36d7c550ebb92c719858d6323a7eed' 
  AND token = 'EK8wPok3Z+8hmd2qg+h5KeK3sIU2qXJf6GZ0Kmz5yTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}