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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '751685770290a1962031c6e75dd6e79b1d1831af87e8933826bd34c77de74719' 
  AND token = 'GaTBDOEkiRF0hIg4w2wbAADma9S6QimnCzdfmZuSdP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}