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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22449c64aec4b486a6bf3aa9a484cf2be9991fca9b3a0a683ab6f57360fed491' 
  AND token = 'Em1+5NMvqgF5+0TAOONZsRleIpdGo+/pbr2AX65uJ5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}