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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af7ad3a9c3d6962dea10efba7f5c76711ec5e47ffdc9d1f05420f677f55fd75' 
  AND token = 'uziIqBJeQ5dCCWu1/EyYQsOHDGOvZ3uBXSB8lHDJg+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}