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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57339fa4b31814702340e57af496db8da79905f05951a5064d5b5b1e758f0ed8' 
  AND token = 'QyZQbxHiaz4uhzE4RcADKd6VFUKqk0A/Yo6rEjFtttU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}