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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac18a392b2443923cf489fda36df2eea7560dacc87bf318984a23f8c913cdc7e' 
  AND token = 'f/8gLouuQm+a434z9LpVxeORcYXCSUmahHCAGTjzXP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}