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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '799de81c7ae939245530ae2d4d17dea8b1d05679df2bed0ed090fc253a352129' 
  AND token = 'ZvAgE5lPosIAjHd+EOQzkRkIGfZoGwjKwTTn4LolQ9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}