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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '577024a2fee15b352220abc358308d271688d445d0b2dd456eca25782bb4d424' 
  AND token = 'Mry/NgxDCUfESq3A8PHcr6lv1e9EekiOgnn3gFHM1GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}