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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e2e345bf51c455550a7568abd9ed1754de7e2172f43c792592afbb09c94eec6' 
  AND token = 'FiiYiZGhIvpcS06PvgU1TB3qzeaVDIVsoGl3aWPcIqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}