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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '270a6218a05f1be65e2a8eae4b00afa2b4b0975dcd8eb65b1313d83863df0606' 
  AND token = 'i1eNzNxPC33r5i1oo86tUxBqTyDAwsFuC6aPzHannJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}