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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08afd30e94f6f3bcf8f6f4bb9364794a59ad516b978d6fbdd5d6342eb8b1b05f' 
  AND token = 'NukhPa1tk8UsnA8bTl02qK6gWgOBbA0EFK+DXrPL7EQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}