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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a2e0ba8fdbeadb59aa27667e8d2b19604331117ed310cb539dc3a466d890c00' 
  AND token = 'CcSZmOxaW22j666VvzZZp0XU4sLqa47jPoJWOPpZUyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}