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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf6728a7a28107a95e4faebc3848ab697e467f966498e9aeab3731b4e78af378' 
  AND token = 'gBkxz7jYLPJ8agOR0iIgk4TPQ+ZIAMVQTAMw0Js0Tss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}