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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '204256a74f61715acef424f71e46005eef1fbe3c2886033755da6d258516b670' 
  AND token = 'KM/t1TxBf/QODz4lFd9n7b8C3Y3GNNnLUSXYARzFLYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}