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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7d5bef137a4b759002070098ec8ae31d9435c39db49b53e536d2c69edd9937e' 
  AND token = 'uvTemAcD/93kmiCqm7tFBSJCCrBJaTRZIV4us/HoZZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}