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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a682a9e0ed602a7702b89a669f2fc4ed7b51bd9984e21e65bbc8b781ca1f24bd' 
  AND token = 'Uwk1dcaAUH4Y0N84KN20sS10bUBPb8Q5wgtsv6NCebo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}