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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5dee5cb9d472d7093e795d4c256351486ccc0fd2426965339e01bff5f3da457' 
  AND token = 'PKcNyzmJv++gNbfRV25rRLJVXw6bZbgSM3x95a34Lds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}