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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e97ee60a97d1b70cd99bea569cc249b91ba3244f0eed8418ad304e2ad09289' 
  AND token = 'had/uhENvZUthaAwT+uFiG6g1y+j7nzRomLshxNGuEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}