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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e245c4f6eb80b2069d141a062e75a558a8129fa3122be9311144f66eba834493' 
  AND token = 'oI+nKCSUGyV14M4JWz7hn//LSpGbqmKh3Mm1m0gsQcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}