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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '529f4deebde04c6f8fc68c5def655f4649eef3bc233500a4355b46d46dd6d11c' 
  AND token = 'e5wbAqrIC/YhaO/nVPj1mZQku2+ch+X20zeqw8KuKD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}