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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a54a0df8034967ac62707ba64dce9a6906a2bbf1f9542ebd989c3e9cab24645' 
  AND token = '4dQrzuGer3OwD09j1gakrBxz0lwv8IIOUcbIjnX8Pjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}