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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '649e6314c60e05d5857c544eb058c2e4f7322fa67e804e8561d4c1af2bf67fa9' 
  AND token = 'MHNRp/dFWwtN1DY9Vcwe5Y4YSBG8BBicTC95Wv38MDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}