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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '227f053faae0eabc3a7c7e955ea5ef7da9f3b3df87533bba0763ece278cbf114' 
  AND token = 'J78tfGiv/F1j5KE2OzaLkCY4F5FGlmciyC6OjHIzAuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}