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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd99b8f57a221d9dd724a8d624ba78b5bd6c1529665deeab60a72947745010752' 
  AND token = 'g3IufTFOJfIDvBDL8jutpZiW2XbB27tsAF/xX9YdeUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}